At approximately 04:40hrs Truck 21 (Jones) was sent to check the area of 2700 Main St. for smoke in the area.. While checking the area a column was seen sending Truck 21 into the Kingsway Subdivision and eventually Queens Ct. Upon turning into the block Truck 21 advised they had a 1-story SFD with fire thru the roof and requested the box be transmitted. With first hand line stretched to the B exposure the E/O established a water supply and set-up for ladder pipe operations. With the main fire building knocked down and exposures covered crews transitioned to interior hitting remaining hot spots and awaiting investigators. Upon completion of assignments and assisting investigators all units returned to service.