At 12:22hrs Truck 21 was dispatched to the 2800 block of Fifth St. for a report of puppies in the storm drain. Upon arrival bystanders reported multiple puppies in the concrete below grade storm drain. With man hole covers welded shut the crew, and along with Engine 23, used saws to gain access and enter the concrete structures. With puppies being puppies they moved away from the noise to the opposite end of the interconnected pipe requiring FF M. George to enter the pipe to retrieve the 4-puppies safely. After clearing both storm drain boxes and piping personnel, along with Fort Bend County Animal Control and Sheriffs Deputies, accounted for all the missing puppies and returned to service approximately an hour later.