At 07:24hrs units were dispatched to the reported vehicle versus a building in the 12600 block of US59. Upon arrival of Battalion 21 an unconscious female driver presented in a pick-up truck having come off the main lanes of US59, striking multiple objects and coming to rest after hitting a large palm tree. With the driver not breathing Battalion 21 and an SPD officer removed her from the vehicle and began CPR as Engine 23 was arriving. With patient care being provided by Engine 23 and FBCEMS Medic #3 the patient was packaged and transported to Memorial Herman Southwest Hospital. Upon completion of assignments all units returned to service. The cause of the accident is under investigation by the Stafford Police Department.